The Advanced Microscopy Facility (AMF) is the imaging core facility of the Sainsbury Wellcome Centre, UCL. The AMF runs the equipment and pipelines through which all the Centre’s microscopy samples are processed. We focus on high-throughput, automated, solutions that are customised for the needs of our researchers. We design, build, upgrade, and repair a variety of custom equipment throughout the SWC. Our tools are designed in the open and used by researchers worldwide.